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Nov 24, 2020

If you had the chance to slow down the aging process, would you take it? This sci-fi concept may sound like something from a Star Trek episode. But with new research coming to light, anti-aging fiction could very soon be a reality. Maybe it’s all in the genes. 


On this podcast, you’ll hear me, Darin Olien, “the superfood hunter,” have honest conversations with the extraordinary people that inspire me. I hope that through their knowledge and unique perspectives, they’ll inspire you, too.

Although our ideas and approaches to life may differ, our ultimate goal is the same- to save the planet one conversation at a time. So, if you’re interested in expanding your view of the world by learning new perspectives on health, nutrition, and healing the planet, this podcast is for you.

Dr. David Sinclair is trying to put a stopper in the aging process.

In fact, he’s the one leading the charge. David is the Australian-born Harvard Medical School professor of genetics. He’s also co-director of the Paul F. Glenn Center for the Biology of Aging Research at Harvard Medical School. 

On top of all that, he’s also a Professor and Head of the Aging Labs at UNSW, Sydney, and an honorary Professor at the University of Sydney. Like many pioneering scientists, he hasn’t been immune to controversy. But, if you Google his name, you’ll see a laundry list of accolades. Especially within the area he’s best known for is, which are genes and small molecules that delay aging.

He is currently spearheading the research into gene function in the aging process, with a really heavy focus on the Sirtuin genes. 

Dr. Sinclair and his team are also trying to lift the lid on exactly what roles resveratrol and NAD precursors play in the anti-aging process. Alongside this, David has published over a whopping 170 scientific papers, is a co-inventor on over 50 patents, and co-founded multiple biotech companies in the areas of aging and biodefense. 

Oh yeah, and he’s the author of Lifespan: Why We Age and Why We Don’t Have To, which shot him to number 11 on the New York Times bestseller list in just over a week. One of David’s most recent claims to fame was his selection to be one of Time Magazine’s 100 Most Influential People In The World. Now that is impressive. 

In this conversation, Dr. Sinclair and I get right into the fantastic family of proteins known as Sirtuins and their role in the aging process. We also look at how Intermittent Fasting could turn back the clock. We get into how it all started with yeast cells, and why David is so interested in the NMN molecule.

Other great topics we cover:

  • The role Sirtuin genes play and why they’re so bossy
  • Epigenetics and why biological stress isn’t such a bad thing
  • Intermittent fasting and what skipping a meal can do for your body
  • What is Resveratrol and how does it affect the body?
  • Why the NAD molecule is so vital for every living organism
  • The Zombie cells that wreak havoc on your health
  • What David is so excited about for the future of anti-aging science
  • Epigenetic reprogramming and reversing the ticking clock inside us all
  • David’s take on stem cells and how they contribute to the aging process
  • When you should really start taking care of your body


David on Facebook

David on Twitter

David on Instagram – @davidsinclairphd

David Sinclair Lab – Harvard Medical School

Lifespan Website - Be sure to sign up for Dr. Sinclair’s Newsletter!

Paper on Olive Oil and SIRT-1 Activation 

Netflix’ Down To Earth’ Official Trailer

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The Darin Olien Show is produced by the team at Must Amplify. If you’re looking to give a voice to your brand, and make sure that it’s heard by the right people, head to to see what Amplify can do for you.